Archive for October, 2009

John Gurdon and Shinya Yamanaka awarded with the 2009 Albert Lasker Basic Medical Research Prize

Sunday, October 18th, 2009
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2009 Lasker Basic Medical Research Awards to John Gurdon and Shinya Yamanaka

2009 Lasker Basic Medical Research Awards to John Gurdon and Shinya Yamanaka

The 2009 Albert Lasker Basic Medical Research Prize has been awarded to John Gurdon (University of Cambridge) and Shinya Yamanaka (Kyoto University), “for discoveries concerning nuclear reprogramming, the process that instructs specialized adult cells to form early stem cells — creating the potential to become any type of mature cell for experimental or therapeutic purposes“.

John Gurdon pioneered nuclear reprogramming experiments in frogs in the 50s and 60s. In 1966, he obtained the first adult fertile frog from nuclear transfer experiments accomplished with larval intestinal cell nuclei. Forty years later, in 2006, Shinya Yamanaka discovered a reduced set of genes that were sufficient to transform a somatic cell into a pluripotent, thereby producing the first induced pluripotent stem cells, or iPS cells. The acceptance remarks and the associated Nature Medicine assays written by John Gurdon and Shinya Yamanaka are most interesting, worth reading and enjoying.

ISTT in social webs

Friday, October 16th, 2009
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ISTT in social webs

ISTT in social webs

The International Society for Transgenic Technologies (ISTT) is now present in a number of social webs. You will find ISTT in YouTube, in Facebook, in LinkedIn and in Twitter. Look for ISTT in your most favourite social web, join in or follow its posts and keep tuned with all activities organised by ISTT.

ISTT videos now available in Flash format

Thursday, October 8th, 2009
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The entire collection of educational ISTT videos illustrating a number of routine techniques in animal transgenesis, and available only to registered ISTT Members, has been now recoded to FLASH format (i.e. the format that it is used in popular video pages such as YouTube). This should allow better enjoying these videos through the ISTT web site.

You can browse an example of it through one of these videos, prepared by Johannes Wilbertz (KI, Stockholm), and showing the microinjection of mouse ES cells into a mouse blastocyst. This video is now available through YouTube as well.

Aimee Stablewski elected new member of the ISTT Council

Wednesday, October 7th, 2009
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Aimee Stablewski

Aimee Stablewski

Aimee Stablewski, Facility Assistant Director of the Gene Targeting and Transgenic Resource at the Roswell Park Cancer Institute, in Buffalo, NY, USA, has been elected new member of the ISTT Council. After the second round of this unexpectedly long election process Aimee received the support of the majority of ISTT members that voted. On behalf of ISTT, congratulations Aimee!. Elizabeth Williams, the second candidate competing in this second round contest, received also a very good support from ISTT membership. Both candidates need to be thanked for their willingness and compromise, and their most generous participation in this election process.

ISTT Survey on Production of Transgenic Mice has been closed

Saturday, October 3rd, 2009
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ISTT Survey on Production of Transgenic Mice has been closed

ISTT Survey on Production of Transgenic Mice has been closed

The ISTT Survey on Production of Transgenic Mice was closed on September 30th, 2009. We will now process all raw microinjection data collected and will try making the best use of them, with the help of our associated statistician Laura Barrios, from CSIC.

We have managed to collect: 85 facilities registered, 66 facilities submitted data, 86 sets of data submitted. This is not close to 100 facilities submitting data, as we aimed for, but still a respectable number of facilities that, hopefully, will be enough to extract all sources of variability and generate a number of interesting conclusions, trends and suggestions that could be of help to all submitters and, also, to anyone interested in generating transgenic mice.

Thanks to all of you that contributed with your raw microinjection data. As indicated, all submitters will be contacted, independently, with a customized analysis of their data. Tom Fielder has been invited to present the outcome of these analyses in Berlin, at the next TT2010 meeting. Therefore, don’t miss his talk and do register to attend the next Transgenic Technology meeting!


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