A manuscript entitled “Genetic polymorphisms among C57BL/6 mouse inbred strains” has been just published by Esther Zurita, Mónica Chagoyen, Marta Cantero, Rosario Alonso, Anna González-Neira, Alejandro López-Jiménez, José Antonio López-Moreno, Carlisle P. Landel, Javier Benítez, Florencio Pazos and Lluís Montoliu in Transgenic Research. The Illumina® Mouse Medium Density Linkage Mapping panel, with 1,449 single nucleotide polymorphisms (SNPs), was used to genotype individuals from ten C57BL/6-related strains: C57BL/6JArc, C57BL/6J from The Jackson Lab, C57BL/6J from Crl, C57BL6/JRccHsd, C57BL/6JOlaHsd, C57BL/6JBomTac, B6(Cg)-Tyr (<c-2j>)/J, C57BL/6NCrl, C57BL/6NHsd and C57BL/6NTac. Twelve SNPs were found informative to discriminate between the “/N” and “/J” C57BL/6 mouse substrains considered. These results will be instrumental for the correct genetic monitoring and appropriate mouse colony handling of different transgenic and knockout mice produced in distinct C57BL/6 inbred substrains. The SNP raw data are also available from the Mouse Phenome Database at Jackson Laboratory.
Archive for the ‘TT meeting’ Category
Genetic polymorphisms among C57BL/6 mouse inbred strains
Monday, May 31st, 2010Report of the TT2010 meeting published in Transgenic Research
Thursday, April 29th, 2010The scientific report corresponding to the 9th Transgenic Technology meeting (TT2010), recently held in Berlin, Germany, at the MDC, in March 22-24, 2010 has been published, as online first article (DOI 10.1007/s11248-010-9397-2, published online, 24 April 2010), in the scientific journal Transgenic Research, associated to ISTT. This meeting report has been prepared by Thom Saunders (Univ. Michigan, Ann Harbor, MI, USA) and Peter Sobieszczuk (Univ. Miami, FL, USA). Thom and Peter will be the organizers of the next 10th Transgenic Technology meeting (TT2011), to be held in Miami, Florida, on October 24-26, 2011.
400 members !!!
Thursday, April 8th, 2010The International Society for Transgenic Technologies (ISTT) has reached today 400 members registered. After a most succesful 9th Transgenic Technology meeting, TT2010, held in Berlin a couple of weeks ago, attended by more than 450 participants and setting a new record for this meeting series, today we have reached the number of 400 members that have subscribed to our Society, four years after it was founded, in January 2006, in Madrid (Spain) with a lot of hope, work and committement by a short list of excited pioneers, but also with trust on a great community of colleagues, interested in animal transgenesis, involved in the production and/or the analysis of them, that we always thought will come along, as it has been the case. Congratulations to everyone and thanks a lot to all ISTT members for their support to this Society.
TT2010 presentations available from the ISTT web site
Saturday, April 3rd, 2010Some of the talks presented at the past TT2010 meeting are now available for visualization from the members-only area of the ISTT web site, a section restricted to ISTT members. As many as 14 presentations have been already contributed by the respective invited speakers, who kindly agreed to share their talks for ISTT members use. If you would like to browse these presentations and you are not yet a member of ISTT we warmly invite you to join our Society. To register as ISTT member, please visit the JOIN section and follow the indications provided.
TT2010: a lively and enjoyable meeting
Saturday, March 27th, 2010The TT2010 meeting is over. More than 460 registered participants (about half of them members of ISTT) attended the past 9th Transgenic Technology meeting, organized by the ISTT, at the MDC, in Berlin-Buch, Germany. The conference itself (March 22-24) was followed by two dedicated workshops on “Colony Management Database Solutions” (March 25) and a practical “Hands-on” course on basic techniques in animal transgenesis (March 25-26). Prof. A. Francis Stewart was awarded the 7th ISTT Prize, sponsored by genOway, for his outstanding contributions in the field of transgenic technologies. He delivered a delightful talk on his work on site-specific recombinases and recombineering over the past 20 years, delineating all the tools his lab has been providing to the scientific comunity that have become central for most post-genomic era applications.
Boris Jerchow, Chair of the TT2010 Organizing Committee, and his team must be congratulated for all their dedication and hard work over the past months that resulted in a lively and enjoyable meeting. The conference was full of discussions and, thanks to the careful talks prepared by all invited speakers, everybody could learn many different aspects of animal transgenesis at different levels, from basic technical or fundamental issues, to more ellaborated and sophysticated scientific applications. Berlin was a great venue for the TT2010 meeting. Such a cosmopolitan city, rich in history, events and locations, was a wonderful complement for social and cultural sightseeing besides the scientific and technical expectations of the TT2010 meeting itself.
Now the TT2010 meeting is over. But ISTT has already started preparing the next forthcoming TT meeting, TT2011, that will be held on October 24-26, 2011, in Miami (Florida, USA), organized by Peter Sobieszczuk and Thom Saunders. All information regarding the TT2011 meeting will be available at the official web site.
One week for the TT2010 meeting…
Monday, March 15th, 2010The TT2010 meeting will start exactly in one week, on March 22, at the Conference Centre of the Max-Delbrück-Center (MDC), in Berlin-Buch, Germany. You can check the latest information about this meeting in its dedicated web site. More than 450 participants will gather in Berlin to discuss the latest technological developments on the generation and the analysis of genetically modified animals. If you are planning to attend and would like to know what will be the weather like in Berlin during the conference you might wish to check the web setion, within the ISTT web site, dedicated to the TIME and WEATHER conditions of several cities around the world with ISTT members, including Berlin. In short, it’s going to be cold, but I am sure we will compensate the outside temperature with a warm welcome and a most enjoyable meeting.
ISTT embryo handling device
Wednesday, March 10th, 2010In Berlin, at the next TT2010 meeting, at the ISTT booth, we will be distributing, as a compliment for all ISTT members attending this conference, the ISTT embryo handling device, a useful tool for mouth pipetting and handling embryos, that can be easily assembled from standard labware parts, along with the corresponding ordering & assembly instructions for those of you willing to prepare new or additional devices. This device is helpful because the firm glass Pasteur pipet provides support for the hand of the technician performing implants. As well, on the rare occasions where too much media is sucked into the implant/transfer needle, the rubber tip can be carefully removed, and additional media sucked into the open end of the Pasteur pipet to recover embryos. The ISTT embryo handling devices have been kindly assembled by Jan Parker-Thornburg (MD Anderson Cancer Center, Houston, TX, USA). There will be additional ordering & assembly instructions at the ISTT booth, for all delegates attending the TT2010 meeting. The instructions document can also be found and downloaded from the members-only section of the ISTT web site.
Program and abstracts of the TT2010 meeting published in Transgenic Research
Wednesday, March 3rd, 2010The program and abstracts of the forthcoming 9th Transgenic Technology meeting (TT2010), to be held in Berlin, at the MDC, on March 22-24, 2010, have been just published in the April issue (19:2) of the scientific journal Transgenic Research, associated to the International Society for Transgenic Technologies (ISTT). All participants registered to attend the TT2010 meeting will receive a complimentary copy of this issue of the journal in Berlin. All ISTT members are entitled for the free access to browse and download this and other articles published in Transgenic Research through the privileged entry point available from within the members-only section of the ISTT web site.
The ISTT Prize: a piece of art created by Bela Rozsnyay
Monday, February 8th, 2010The International Society for Transgenic Technologies (ISTT) has established a “Prize for outstanding contributions to the field of Transgene Technologies“. The ISTT Prizes are awarded at each Transgenic Technology (TT) Meeting and are generously sponsored by genOway. The ISTT Prize is a unique piece of art and represents a mouse blastocyst created in silver by the Hungarian artist Mr. Bela Rozsnyay.
Next ISTT Prize will be awarded in Berlin, at the TT2010 meeting, to Prof. Francis Stewart ( TU Dresden, Germany). Previous awardees of this ISTT Prize have been: Brigid Hogan (TT2008), Charles Babinet (TT2007), Andras Nagy (TT2005), Qi Zhou (TT2004), Kenneth J. McCreath (TT2002) and Teruhiko Wakayama (TT2001). All awarded ISTT Prize winners are given Honorary ISTT Membership.
Registration for the TT2010 meeting has been closed
Thursday, January 28th, 2010Registration for attending the next TT2010 meeting is no longer possible. We thank for your interest. We have reached the maximum number of participants that are allowed at the MDC venue. If you have any question, comments or doubts, please contact the TT2010 Registration Office at tt2010@transtechsociety.org.
TT2010 Organizing Committee
Berlin, 28 January 2010














