Archive for the ‘co-sponsorhip’ Category

Feng Zhang receives his ISTT Diploma as Young Investigator Awardee

Sunday, November 9th, 2014
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Feng Zhang (BROAD institute-MIT) receives his ISTT Diploma as Young Investigator Awardee from Changhong Pang (ingenious targeting laboratory)

Feng Zhang (BROAD institute-MIT) receives his ISTT Diploma as Young Investigator Awardee from Changhong Pang (ingenious targeting laboratory)

The 3rd ISTT Young Investigator Awardee, Feng Zhang (BROAD institute, MIT) receives the ISTT Diploma from Changhong Pang (ingenious targeting laboratory) in his lab, at the BROAD institute, after the TT2014 meeting held in Edinburgh. Congratulations to Feng Zhang and many thanks to ingenious targeting laboratory for their generous support to these ISTT Young Investigator Awards!

CARD-RPCI Cryopreservation Course Report

Monday, September 22nd, 2014
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CARD-RPCI Cryopreservation Course Report

CARD-RPCI Cryopreservation Course Report

During the past week, 15-19 September 2014, the CARD-RPCI Mouse Sperm and Embryo Cryopreservation Course was held at Roswell Park Cancer Institute, in Buffalo, NY, USA, organized by Naomi Nakagata (CARD-Kumamoto University, Japan), Aimee Stablewski (Roswell Park Cancer Institute, Buffalo, NY, USA) and Jan Parker-Thornburg (MD Anderson Cancer Center, Houston, TX, USA). This was the second CARD course organized overseas, outside Asia, after the first course organized in Madrid in October 2013. This new practical course in North America was co-sponsored by the International Society for Transgenic Technologies (ISTT). What follows is a brief course report prepared by Aimee Stablewski and Jan Parker-Thornburg, who deserve to be praised, along with Naomi Nakagata and his CARD team, for another most successful cryopreservation course. This course report can also be downloaded from here.

CARD-­RPCI Spermand Embryo CryopreservationWorkshop
September 15-­19, 2014
Roswell Park Cancer Institute, Buffalo NY, USA

MEETING REPORT

The CARD-RPCI Sperm and Embryo Cryopreservation Workshop was recently held in Buffalo NY USA on the campus of Roswell Park Cancer Institute. Eighteen trainees, fifteen instructors and lecturers, and numerous vendors were hosted by Naomi Nakagata (Kumamoto University), Aimee Stablewski (Roswell Park Cancer Institute) and Jan Parker-Thornburg (MD Anderson Cancer Center) from September 15-19, 2014. Drs. Naomi Nakagata and Toru Takeo brought their team from CARD to assist the trainees in learning the latest techniques in embryo vitrification, sperm cryopreservation, in vitro fertilization, and the new method of vitrifying oocytes. In addition, Jorge Sztein instructed the trainees in methods of ovary freezing and subsequent implant after thaw; Lluis Montoliu provided lectures in current methods of embryo cryopreservation and CRISPR/Cas9 methods of generating genetically engineered mice, and Barbara Stone provided training in using the NSET method of embryo implant.

This was the first time that the CARD team provided training in North America, and the team (supported by Kumamoto University and Kyudo Co., LTD.) delivered a truly memorable experience for the trainees. Hands-on sessions were intense and intended to provide trainees with the knowledge and experience of performing the exacting CARD techniques. The eighteen trainees were composed of fourteen ISTT members and four non-members. Of these, three were from Europe, one from Australia, one from New Zealand, and the remainder from all parts of North America.

Hands on training included isolating unfertilized mouse oocytes, isolating and cold storage/shipping of mouse cauda epididymis, freezing/thawing mouse sperm and IVF using CARD frozen sperm and legacy sperm, fresh mouse sperm and IVF, cold stored sperm and IVF, freezing/thawing 2-cell IVF-derived mouse embryos, vitrification of mouse oocytes and embryos, IVF of vitrified mouse oocytes, ovary transplantation/ovary freezing, and embryo transfer techniques in mice (oviduct, uterus via NSET).

Didactic lectures were given on the topics of historic and scientific perspectives of embryo and sperm cryopreservation (by Jorge Sztein), comparing current embryo and sperm cryopreservation methods (by Lluis Montoliu), vitrification of oocytes and their use for IVF (by Naomi Nakagata), new US guidelines for the use of animals in research/IACUC (by Sandra Sexton), CRISPR/Cas9 and gene editing endonucleases (by Lluis Montoliu), development of database for managing mouse banking system (by Shuuji Tsuchiyama), shipping mice, frozen or refrigerated embryos/sperm across the world (by Toru Takeo) and freezing and transplantation of ovaries (by Jorge Sztein).

On Wednesday of the workshop, all of the participants were treated to a trip to Niagara Falls followed by an exceptional gala dinner (arranged by Aimee Stablewski) at a local winery. This short respite enabled the participants to replenish their energies for subsequent long days of IVF, vitrifications and surgery.

In all, it proved to be an exceptional workshop, with all participants achieving exceptional results in most, if not all, of the practicals. In fact, the depth of appreciation for being taught these methods became clear both during the closing session, where all instructors, vendors, and participants thanked Dr. Nakagata with a standing ovation, and immediately afterward, where many compliments were given. Perhaps, one of the participants said it best in an e-mail immediately following the course:

a big thank you to Prof. Nakagata, Dr. Toru Takeo and the entire CARD team. The way they have organised is unbelievable. As we all know in biological practical experiments, how much ever we take care, they never go according to plan and there is always a blooper. I must confess, I had my doubts that we would ever stick to the time table. I am glad that I was completely proven wrong. They have given attention to every bit of details and must have put lot of rehearsals behind this. They were fantastic. They answered all the questions and made sure everyone understood plus followed it up with the practicals. The Entire Card team was simply amazing and no other way to express my gratitude than simply saying “I bow to the entire CARD team”.”
Prasanna Kallingappa
University of Aukland
New Zealand

Aimee Stablewski and Jan Parker-Thornburg, as hosts, would like to acknowledge not only our lecturers, but also the CARD team who assisted the students, including Shuuji Tsuchiyama, Kiyoko Fukumoto, Yukie Haruguchi, Tomoko Kondo, Yumi Takeshita, Yuko Nakamuta, Tomoko Umeno, (all from Kumamoto University and Kyudo Co. LTD); and the CARD “adoptees”—Kristy (Kinchen) Williams (University of Florida) and Amar Dasari (Taconic). In addition, technical assistance was ably provided by Dawn Barnas (ISTT), Karstin Webber, Sandra Sexton and Leslie Curtin (all RPCI), who treated over 600 mice with hormones!

The workshop was extremely fortunate to have extremely generous vendor support, including our platinum sponsors: Charles River Laboratories (who supplied all of the mice used in the course), Leica Microsystems (who provided all of the microscopes used for the course as well as onsite support by Louise Bertrand), and Kyudo Co., LTD who provided support for the CARD instructors as well as onsite support by Nobuyuki Mikoda; our gold sponsors: the ISTT (who sponsored Lluis Montoliu’s participation and contributed to the gala dinner), Taconic (who provided instructional support from John Couse and Amar Dasari), and Regeneron (who sponsored a lecture by Lluis Montoliu); our silver sponsors: Hamilton Thorne (who provided instruction in sperm analysis and laser-assisted IVF by Nancy Mutch), IDEXX Bioresearch for course support, Paratechs for sponsoring Dr. Barbara Stone’s participation, Cell Preservation Solutions who provided course support and Lifor media for cold-storage, CosmoBio who provided course support, Transposagen who provided course support, and our bronze sponsors: Millipore EMD and mofa for equipment, Tokai-Hit for equipment, Eppendorf (Mike Bady) for course support and equipment, and VWR and Sarstedt for course support.

Finally, we thank our participants for their hard work and dedication to bring the newest transgenic technologies back to their institutions.

Aimee Stablewski, Roswell Park Cancer Institute, Buffalo, NY, USA
Jan Parker-Thornburg, MD Anderson Cancer Center, Houston, TX, USA

TT2014 abstracts: submission deadline is approaching (30 June)

Tuesday, June 17th, 2014
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TT2014 abstracts: submission deadline is approaching (30 June)

TT2014 abstracts: submission deadline is approaching (30 June)

From the International Society for Transgenic Technologies (ISTT) we warmly invite and encourage you all to submit your most recent and exciting results and developments in animal transgenesis to be presented at the forthcoming 12th Transgenic Technology (TT2014) meeting, which will be held in Edinburgh, Scotland, UK, on 6-8 October 2014. Deadline for submitting abstracts for the TT2014 meeting is June 30.
To submit an abstract please visit this TT2014 meeting web page.

All TT2014 participants are encouraged to submit their work as an abstract for poster presentation at the TT2014 meeting. Authors are requested to submit an abstract with the following requirements:

  • Title (max. 25 words)
  • Name authors and affiliations (first author is the presenting author).
  • Text of the communication (max. 400 words).
  • Abstracts should be submitted no later than June 30, 2014.

Accepted abstracts will be published in the scientific journal Transgenic Research (Springer), to which the ISTT is associated.

Posters
Posters will be on display in the exhibition area throughout the duration of the meeting. Poster boards are 1.00m wide x 2.00m high and we recommend posters do not exceed 1.50m in length. A supply of Velcro tabs will be available at the venue. No screws or double-sided adhesive tape will be allowed due to the damage they can cause to the boards.

Best Poster Awards
All posters presented at the TT2014 meeting will be eligible for one of the ISTT Best Poster Awards, generously sponsored by Charles River, Inc.

Oral Presentations
A limited number of abstract submissions will be selected and invited to present their findings in the form of a short oral presentation within the main meeting program. Should you be interested in being considered to speak at the meeting please select the appropriate option when submitting your abstract.

Abstracts are invited on all aspects of Transgenic Technologies, including the conference themes as listed below:

  • New technologies in animal transgenesis
  • Embryo stem cells
  • Target nucleases or Editing nucleases (ZFNs, TALENs, CRISPRs)
  • Large-scale phenotyping
  • Animal Biotechnology
  • Imaging with transgenic animals
  • Mouse models of human disease
  • Zebrafish models of human disease and transgenesis
  • Animal ethics and welfare

We are looking forward to receiving your exciting works to discuss the latest development on animal transgenesis!. See you all in Edinburgh!

Submit your abstract(s) to the TT2014 meeting in Edinburgh: 30 June

Sunday, May 11th, 2014
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Submit your abstract(s) to the TT2014 meeting in Edinburgh: 30 June

Submit your abstract(s) to the TT2014 meeting in Edinburgh: 30 June

The submission of abstracts for the 12th Transgenic Technology (TT2014) meeting, to be held in Edinburgh (Scotland, UK), on 6-8 October, is OPEN. All TT2014 participants are encouraged to submit their work as an abstract for poster presentation at the TT2014 meeting. Authors are requested to submit an abstract with the following requirements: Title (max. 25 words), Name authors and affiliations (first author is the presenting author), and, Text of the communication (max. 400 words). Abstracts should be submitted no later than June 30, 2014. Accepted abstracts will be published in the scientific journal Transgenic Research (Springer), to which the ISTT is associated.

Posters
Posters will be on display in the exhibition area throughout the duration of the meeting. Poster boards are 1.00m wide x 2.00m high and we recommend posters do not exceed 1.50m in length. A supply of Velcro tabs will be available at the venue. No screws or double-sided adhesive tape will be allowed due to the damage they can cause to the boards. All presented Posters at the TT2014 meeting will be entitled to the Best Poster Awards, generously sponsored by Charles River.

Oral Presentations
A limited number of abstract submissions will be selected and invited to present their findings in the form of a short oral presentation within the main meeting program. Should you be interested in being considered to speak at the meeting please select the appropriate option when submitting your abstract.

Abstracts are invited on all aspects of Transgenic Technologies, including the conference themes as listed below:

  • New technologies in animal transgenesis
  • Embryo stem cells
  • Target nucleases or Editing nucleases (ZFNs, TALENs, CRISPRs)
  • Large-scale phenotyping
  • Animal Biotechnology
  • Imaging with transgenic animals
  • Mouse models of human disease
  • Zebrafish models of human disease and transgenesis
  • Animal ethics and welfare

The 3rd ISTT Young Investigator Award goes to Feng Zhang

Monday, April 28th, 2014
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The 3rd ISTT Young Investigator Award goes to Feng Zhang (picture kindly provided by the Broad Institute of MIT and Harvard)

The 3rd ISTT Young Investigator Award goes to Feng Zhang (picture kindly provided by the Broad Institute of MIT and Harvard)

The International Society for Transgenic Technologies (ISTT) is pleased to announce the awardee for the third (3rd) ISTT Young Investigator Award, generously sponsored by inGenious Targeting Laboratory (iTL). After careful evaluation of the nominated candidates, the Award Committee selected Dr. Feng Zhang (Broad Institute of MIT and Harvard; the McGovern Institute for Brain Research at MIT; and the Departments of Brain and Cognitive Sciences, and Biological Engineering at MIT, Cambridge, MA, USA).

Zhang’s recent outstanding work in the development of the CRISPR-Cas technology has set the pace in this highly competitive field. Among his many seminal contributions to CRISPR-Cas technology is the engineering of the RNA-guided nuclease Cas9 for use in editing the mammalian genome. This and his other recently published works have clearly impacted the field of transgenic technologies. Moreover, Zhang has encouraged transparency in the development of CRISPR-Cas technology and has made his work accessible for use by the broader scientific community.

Zhang was born in Shijiazhuang (Hebei Province, China) in 1981 and moved to the USA in 1993, where he was educated and trained at various institutes, including the Human Gene Therapy Research Institute (Des Moines, IA, 1997-99) as a high school student and the Department of Chemistry and Chemical Biology (2000-2004) at Harvard University (Cambridge, MA), where he obtained before his A.B. degree in Chemistry and Physics. He then moved to Stanford University (Stanford, CA) to conduct his PhD work (2004-2009) under the supervision of Dr. Karl Deiseroth in the Department of Bioengineering,  obtaining his Ph.D. degree in Chemistry in 2009. As a graduate student, Dr. Zhang worked with Deisseroth to invent a set of technologies for dissecting the functional organization of brain circuits, using light-sensitive proteins from green algae and other microbes to develop a new “optogenetic” toolbox for controlling the activity of neurons in live organisms with light.

After finishing his Ph.D., he returned to Cambridge, MA, as a Junior Fellow at the Harvard Society of Fellows (2009-2010) and began his own laboratory at the Massachusetts Institute of Technology (MIT) in 2011 as an Assistant Professor. He has achieved great success and has shown strong leadership as a Core Member of the Broad Institute of MIT and Harvard; as an Investigator of the McGovern Institute for Brain Research at MIT; and as a W. M. Keck Career Development Professor in Biomedical Engineering, in the Departments of Brain and Cognitive Sciences and Biological Engineering at MIT. Dr. Zhang provides an excellent example of how scientific questions lead to the development and utilization of new technologies, as is reflected by his widespread research as an investigator at these various institutions.

Dr. Zhang has already received numerous prizes, awards and distinctions, including: the Perl/UNC Prize in Neuroscience, the NIH Director’s Pioneer Award, technology innovation awards from the McKnight and Damon Runyon Foundations, and the NSF Alan T. Waterman Award. He was also recently named one of the “Brilliant Ten” top minds in science by Popular Science, and also named by Nature as one of their top 10 scientists who mattered in 2013. Dr. Feng Zhang is also a co-founder of the popular non-profit molecular biology web app everyVECTOR.

The following articles represent only some of his recent research published in the last two years, highlighting his most recent contributions to the CRISPR-Cas field and related publications on other editing nucleases systems. These publications have had a tremendous impact in the animal transgenesis field and have rapidly become highly sought-after references for subsequent studies.

The 2014 ISTT Young Investigator Award Committee was formed by Dr. Lluis Montoliu (President of ISTT), Dr. Benoît Kanzler (Vice-President of ISTT, Chair) and Dr. Paul Sheiffele (iTL CEO). Dr. Feng Zhang was nominated by ISTT Member Dr. Jan Parker-Thornburg (MD Anderson Cancer Centre, Houston, TX, USA).

Dr. Feng Zhang will attend the next 12th Transgenic Technology (TT2014) meeting in Edinburgh (Scotland, UK, 6-8 October 2014) where he will receive the corresponding diploma and will deliver a talk summarizing the scientific achievements that led him to receive this 3rd ISTT Young Investigator Award, sponsored by inGenious Targeting Laboratory (iTL).

Download this Press Release as a PDF document

CARD-RPCI Mouse Sperm and Embryo Cryopreservation Course, Roswell Park Cancer Institute, Buffalo, NY, USA, September 15th-19th, 2014

Monday, March 31st, 2014
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CARD-RPCI Mouse Sperm and Embryo Cryopreservation Course, Buffalo, NY, USA, September 15-19, 2014

CARD-RPCI Mouse Sperm and Embryo Cryopreservation Course, Buffalo, NY, USA, September 15-19, 2014

The International Society for Transgenic Technologies (ISTT) has agreed to co-sponsor another CARD Cryopreservation Course. This time, for the first time, the CARD methods will be taught in North America: the CARD-RPCI Mouse Sperm and Embryo Cryopreservation Practical Course will be held at Roswell Park Cancer Institute (RPCI) in Buffalo, NY USA. The course will be held September 15th-19th, 2014, and will be a hands-on intensive workshop.

The course is organized by Naomi Nakagata (CARD-Kumamoto University, Japan, Coordinator of CARD), Aimee Stablewski (Roswell Park Cancer Institute, Buffalo, NY, USA, Co-Director of the Gene Targeting and Transgenic Resource) and Jan Parker-Thornburg (MD Anderson, Houston, TX, USA, Director of the Genetically Engineered Mouse Facility).

This course is open to anyone interested. Pre-application will be required, including, at least, a recent CV, completion of this application questionnaire, and a letter prepared by the intended participant describing how the applicant will benefit by attending this course and how relevant is the course material to his/her work. Additional documents are welcome, at the discretion of participants, including supporting letters by supervisors (where appropriate), reference letters, etc… Pre-applications should be submitted by email to: buffalo_card_cryocourse@transtechsociety.org

The maximum number of participants attending this course will be 18, distributed among countries and institutions, and according the documentation provided and the interests expressed. Pre-applications will be accepted starting April 1st, 2014 and will close on May 31st, 2014. The review and selection of participants will be done by the Organizers from June 1st-15th, 2014. Registrations and payments for selected participants will be accepted from June 16th, 2014 to August 31st, 2014. If required, an ordered waiting list will be prepared and any cancellation or unpaid registration by August 31st, 2014 will be readily substituted by the first available person from this waiting list, starting on September 1st, 2014.

The course registration fee is $1300 USD (with a reduced fee of $1100 USD for ISTT members). This fee includes participation in the entire course, all materials and reagents, lunches over the 5 days and one course official dinner. Hotel costs are not included in the registration fee but booking assistance will be provided, if required, at a hotel on Roswell Park Cancer Institute’s campus, where all instructors and lecturers will be also lodged, hence further promoting interaction from breakfast to dinner. The official language of the course will be English.

COURSE INFORMATION: Recent developments from the laboratory of Prof. Naomi Nakagata (CARD-Kumamoto University, Japan) have boosted the mouse cryopreservation field with improved methods for fresh and frozen sperm techniques and associated optimized IVF methods that have resulted in unparalleled increased efficiencies for the cryopreservation and rescue of relevant mouse lines.

The aim of this course is to introduce the new CARD methods to researchers and technicians involved in managing mouse archiving and/or transgenic facilities and willing to implement these new methods, directly taught by the team which devised them. Each participant will have one stereomicroscope and the entire set of tools, reagents and animals required to learn and practice all the methods included in the program of this course. In addition to practical sessions, the course will also include several lectures of related interesting topics for the participants delivered by experts in each field. The number of instructors and lecturers appointed is 17.

Hands-on topics that will be covered during this cryopreservation course:

  • Isolating unfertilized mouse oocytes
  • Isolating and cold storage/shipping of mouse cauda epididymis
  • Isolating and cold storage of embryos
  • Freezing/thawing mouse sperm and IVF using CARD frozen sperm and legacy sperm
  • Fresh mouse sperm and IVF
  • Cold Storage sperm and IVF
  • Freezing/thawing 2-cell IVF-derived mouse embryos
  • Vitrification of mouse oocytes and embryos
  • IVF of vitrified mouse oocytes
  • Ovary transplantation/ovary freezing
  • Embryo transfer techniques in mice (oviduct, uterus via NSET)

Additional lectures on the following topics:

  • Historic and Scientific perspectives of embryo and sperm cryopreservation
  • Comparing current embryo and sperm cryopreservation methods
  • Vitrification of oocytes and their use for IVF
  • New US Guidelines for the use of animals in research/IACUC
  • Cold storage and transport of germplasm
  • Large archiving and distribution centers- challenges and solutions
  • Shipping mice, refrigerated and frozen material
  • CRISPR/Cas9
  • Freezing and transplantation of ovaries
  • NSET: non-surgical embryo transfer
  • Breeding strategies for cohort generation of GEM’s
  • CARD

Instructors:

  • Naomi Nakagata (CARD-Kumamoto University, Japan)
  • Toru Takeo (CARD-Kumamoto University, Japan)
  • Shuuji Tsuchiyama (CARD-Kumamoto University, Japan)
  • Kiyoko Fukumoto (CARD-Kumamoto University, Japan)
  • Yukie Haruguchi (CARD-Kumamoto University, Japan)
  • Tomoko Kondo (CARD-Kumamoto University, Japan)
  • Yumi Takeshita (CARD-Kumamoto University, Japan)
  • Yuko Nakamuta (CARD-Kumamoto University, Japan)
  • Tomoko Umeno (CARD-Kumamoto University, Japan)
  • Jan Parker-Thornburg (MD Anderson, Houston, TX, USA)
  • Aimee Stablewski (Roswell Park Cancer Institute, Buffalo, NY, USA)
  • Dawn Barnas (Roswell Park Cancer Institute, Buffalo, NY, USA)
  • Amar Dasani (Taconic, Germantown, NY, USA)
  • Andrea Dunn (Taconic, Germantown, NY, USA)
  • Kristy Williams (USA)
  • Barbara Stone (ParaTechs, Lexington, KY, USA)
  • Jorge Sztein (Barcelona, Spain)

Additional lectures by:

  • Naomi Nakagata (CARD-Kumamoto University, Japan)
  • Toru Takeo (CARD-Kumamoto University, Japan)
  • Sandra Sexton (Roswell Park Cancer Institute, Buffalo, NY, USA)
  • Jorge Sztein (Barcelona, Spain)
  • Barbara Stone (ParaTechs, Lexington, KY, USA)
  • Lluis Montoliu (CNB-CSIC, Madrid, Spain)
  • Carlisle Landel (Transposagen Inc., Lexington, KY, USA)
  • Amar Dasani (Taconic, Germantown, NY, USA)

Updated scientific and workshop programmes for the TT2014 meeting in Edinburgh

Friday, January 10th, 2014
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Upades scientific and workshop programmes for TT2014 meeting in Edinburgh: Please, register today!.

Upades scientific and workshop programmes for TT2014 meeting in Edinburgh: Please, register today!.

The scientific and zebrafish transgenesis hands-on workshop programmes prepared for the 12th Transgenic Technology (TT2014) meeting, to be held in Edinburgh (Scotland, UK), on October 6-8 (workshop on October 8-10) 2014,  have been recently updated by the Organizers, chaired by Douglas Strathdee (Glasgow, UK). These rewarding updates further increased the already high quality and interest for this popular conference series, promoted from the International Society for Transgenic Technologies (ISTT), the most important forum where to discuss the state-of-art of animal transgenic technology, to share new developments, to review the deployment of the new methods that have recently being devised and, in summary, an excellent arena where to easily meet, face-to-face, the most relevant key-players in the field while providing a wonderful excuse to gather and ex-change experiences with the entire ISTT family of members.

The updated list of confirmed invited speakers attending the TT2014 meeting (6-8 October 2014) includes:

  • David Adams, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
  • Ignacio Anegon, Center for Research in Transplantation and Immunology, Nantes, France
  • James Bussell, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
  • Ian Chalmers, MRC Centre for Regenerative Medicine, The University of Edinburgh, UK
  • Stephen Ekker, Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA
  • Anna-Katerina Hadjatonakis, Developmental Biology Program, Sloan-Kettering Institute, New York, USA
  • Peter Hohenstein, The Roslin Institute and Royal Dick School of Vetinary Studies & MRC IGMM, University of Edinburgh, UK
  • Rudolf Jaenisch, Whitehead Institute for Biomedical Research, Nine Cambridge Center Cambridge, USA
  • Jos Jonkers, Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
  • Keith Joung, Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
  • Alexandra Joyner, Developmental Biology Program, Sloan-Kettering Institute, New York, USA
  • Koichi Kawakami, Division of Molecular and Developmental Biology, National Institute of Genetics, Shizuoka, Japan
  • Michael McGrew, Division of Developmental Biology, The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, UK
  • Daniel J Murphy, Beatson Institute for Cancer Research, University of Glasgow, UK
  • James Murray, Department of Animal Science and Department of Population Health and Reproduction, University of California, Davis, California, USA
  • Stephen Murray, The Jackson Laboratory, Bar Harbor, Maine, USA
  • Lluis Montoliu, ISTT President, Organising Committee, National Center of Biotechnology (CNB), CSIC, Madrid, Spain
  • Vasilis Ntziachristos, Technische Universität Mu?nchen, Munich, Germany
  • Elizabeth Patton, MRC Human Genetics Unit & MRC IGMM, University of Edinburgh, UK
  • Pawel Pelczar, Institute of Laboratory Animal Science, Zürich, Switzerland
  • Jan-Bas Prins, Leiden University Medical Centre, The Netherlands
  • Janet Rossant, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada (ISTT Prize)
  • Angelika Schnieke, Livestock Biotechnology, WZW Center of Life Science, Freising-Weihenstephan, Germany
  • Kai Schönig, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany
  • William Skarnes, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
  • Austin Smith, Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK
  • Francis Stewart, Biotechnology Center of the TU Dresden, Germany
  • Sara Wells, MRC Harwell, Oxfordshire, UK
  • Jacqueline White, Wellcome Trust Sanger Institute, Hinxton, Cambridge UK

The updated list of confirmed invited speakers & instructors attending the hands-on zebrafish transgenesis workshop taking place immediately after the TT2014 meeting (8-10 October 2014) includes:

  • Liz Patton, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh
  • Carl Tucker, Biomedical Research Resources, The University of Edinburgh
  • Tim Czopka, Centre for Neuroregeneration, The University of Edinburgh
  • Koichi Kawakami, Division of Molecular and Developmental Biology, National Institute of Genetics, Shizuoka, Japan
  • Stephen Ekker, Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA
  • Keith Joung, Department of Pathology, Massachusetts General Hospital and Harvard Medical School
  • Henry Roehl, Department of Biomedical Science, The University of Sheffield
  • Robert Kelsh, Centre for Regenerative Medicine and Department of Biology and Biochemistry, The University of Bath
  • Martin Denvir, The University of Edinburgh/British Heart Foundation Centre for Cardiovascular Science, The University of Edinburgh
  • David Lyons, Centre for Neuroregeneration, The University of Edinburgh
  • Dirk Seiger, Centre for Neuroregeneration, The University of Edinburgh
  • Karthikeyani Paranthaman, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh

Abstracts: All TT2014 participants are encouraged to submit their work as an abstract for poster presentation at the TT2014 meeting. Abstracts should be submitted no later than June 30, 2014. Accepted abstracts will be published in the scientific journal Transgenic Research (Springer), to which the ISTT is associated. A limited number of abstract submissions will be selected and invited to present their findings in the form of a short oral presentation within the main meeting program. Abstracts are invited on all aspects of Transgenic Technologies, including the conference themes as listed below:

  • New technologies in animal transgenesis
  • Embryo stem cells
  • Target nucleases or Editing nucleases (ZFNs, TALENs, CRISPRs)
  • Large-scale phenotyping
  • Animal Biotechnology
  • Imaging with transgenic animals
  • Mouse models of human disease
  • Zebrafish models of human disease and transgenesis
  • Animal ethics and welfare

Registration for both the TT2014 meeting and the zebrafish transgenesis workshop are OPEN. Registration for the TT2014 meetings starts at 265 UK Pounds for technician/student ISTT members and progressively increases for the rest of categories of delegates. ISTT members are always entitled to reduced registration fees. Registration for the zebrafish transgenesis workshop is independent, with an extra cost of 275 UK Pounds , and only open to delegates that have also registered to attend the TT2014 meeting. The early bird reduced registration fees are operative until July 31, 2014. Thereafter, registration will be progressively become more expensive. Hence,  please register by July 31, 2014 to benefit from reduced registration fees.

ISTT Registration Awards: Application to ISTT registration awards for the TT2014 meeting is OPEN. A minimum of six registration awards for ISTT members will be sponsored by the International Society for Transgenic Technologies (ISTT). Applications should be sent, along with the registration confirmation and the requested additional documents to istt@transtechsociety.org by June 30, 2014. The ISTT will pay the Registration Fee of all applicants selected for an award. Please note that applicants not selected for an award are required to pay the coresponding registration fee. Please note the Award covers registration fees and attendance at all social events, however, does not cover travel, accommodation expenses or attendance at pre meeting events. Award decisions will be communicated by July 15, 2014 and awardees will receive a diploma at the TT2014 Meeting. Deadline for submitting application for ISTT Registration Awards for TT2014: 30 June 2014. Registration Award decisions will be communicated by 15 July 2014.

Looking forward to meeting you all in Edinburgh!

 

Third ISTT Young Investigator Award

Saturday, January 4th, 2014
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Third ISTT Young Investigator Award

Third ISTT Young Investigator Award

The International Society for Transgenic Technologies (ISTT), in collaboration with inGenious Targeting Laboratory (iTL), has established the ISTT YOUNG INVESTIGATOR AWARD that is presented at each Transgenic Technology meeting. The third edition of this ISTT Young Investigator Award will be given at the next 12th Transgenic Technology Meeting (TT2014), that will be held in Edinburgh, on 6-8 October 2014.

The ISTT Young Investigator Award recognizes outstanding achievements by a young scientist who will keep the field of transgenic technologies vibrant with new ideas and who has recently received his or her advanced professional degree. The ISTT Young Investigator Award is generously sponsored by inGenious Targeting Laboratory (iTL).

To date, two editions of the ISTT Young Investigator Awards have been already granted to Dr. Xiao-Yang Zhao (China) and Dr. Toru Takeo (Japan), at the corresponding TT2011 and TT2013 meetings, respectively.

The ISTT Young Investigator Award is associated to funds that will serve to defray the costs related to the participation of the ISTT Young Investigator awardee at the corresponding TT Meeting, including: TT meeting registration fee, travel expenses to the TT meeting venue and accommodation during the meeting dates for the awarded candidate, with a maximum being set to 1500 Euros. All ISTT Young Investigator awardees will be given 1 year Ordinary ISTT Membership and a diploma, that will be provided at the ISTT Awards Ceremony, within the TT Meeting Program.

Instructions for participating and additional information are provided at the ISTT Young Investigator Award web page, within the ISTT web site.

ELEGIBILITY criteria for ISTT Young Investigator Awards

Nominees must be active in research, in the field of transgenic technologies, at the time the award is given. Nominees must have received a PhD or MD (or equivalent) within the past 10 years.

NOMINATION criteria for ISTT Young Investigator Awards

Nominations must be made or endorsed by an ISTT member. Nominee does not have to be an ISTT member. Self nomination is not permitted. No person may nominate more than one candidate.

PROCEDURE for participating in the ISTT Young Investigator Awards selection process

Nominations must be made or endorsed by an ISTT member and should include:

  • the CV of the nominee
  • a document highlighting the achievements made by the nominee in the field of transgenic technologies
  • a message or document confirming the nominee’s acceptance to participate in the ISTT Young Investigator Award selection process

All documents should be sent by the ISTT Member nominating the candidate to the ISTT email address: istt@transtechsociety.org

Currently we are accepting nominations for the 3rd ISTT Young Investigator Award for the TT2014 meeting in Edinburgh.

DEADLINE for submitting nominations: March 29, 2014.

Decision for the TT2014 ISTT Young Investigator Award will be communicated by May 31, 2014.

On behalf of the ISTT, I would like to thank inGenious Targeting Laboratory for their support to the ISTT and, in particular, for sponsoring this 3rd  ISTT Young Investigator Award.

With my best regards,

 Benoît Kanzler

ISTT Vice-President

ISTT Best Poster Awards at TT meetings sponsored by Charles River

Sunday, November 10th, 2013
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ISTT Best Poster Awards at TT meetings sponsored by Charles River

ISTT Best Poster Awards at TT meetings sponsored by Charles River

The International Society for Transgenic Technologies (ISTT), in collaboration with Charles River Laboratories International, Inc. (CRL), has establised the ISTT BEST POSTER AWARDS that will be given at the Transgenic Technology (TT) Meetings. The ISTT Best Poster Awards recognize outstanding work presented by participants at Transgenic Technology (TT) meetings. The ISTT Best Poster Awards are generously sponsored by Charles River Laboratories International, Inc. (CRL).

All posters accepted and presented at a TT meeting will be eligible for these ISTT Best Poster Awards. An ISTT Best Poster Awards committee will be established by the ISTT in order to select the awarded posters among among all presented communications submitted to a TT meeting as Posters. This committee might include members of the ISTT Council, members of the Local Organizing Committee and any other willing ISTT member and will have a Chair. The ISTT Council will nominate the members of this Committee and its Chair. The number of Posters to be awarded might vary, from TT meeting to TT meeting, although the figure of selecting the three best posters presented might be used as a reference. The scientific and technical quality of the Poster, he novelty of the results presented, as well as the artwork applied and the overall layout of the Poster will be judged by this Committee, among any additional criteria, at its sole discretion. The ISTT will define the nature of the presents to be given to the presenters of the selected awarded Posters.

The next TT meeting where the ISTT Poster Awards will be given is the 12th Transgenic Technology meeting, TT2014, to be held on 6-8 October 2014 in Ediburgh, Scotland, UK.

The TT2014 meeting web page has been launched: REGISTRATION IS OPEN!

Thursday, October 31st, 2013
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The TT2014 meeting web site has been launched. REGISTRATION IS OPEN!

The TT2014 meeting web site has been launched. REGISTRATION IS OPEN!

Today, the 12th Transgenic Technology (TT2014) meeting web site has been launched. And meeting registration is already open!. The TT2014 meeting is organized by ISTT members Douglas Strathdee-chair, Peter Hohenstein and Bruce Whitelaw and will be held at The Assembly Rooms, in Edinburgh, Scotland, UK, on 6-8 October 2014. Immediately following the TT2014 meeting, on October 9-10, 2014, there will be a hands-on practical workshop called ‘An Introduction to Zebrafish Transgenesis‘ which will focus on Zebrafish.  Further details about this practical workshop will be announced at the TT2014 meeting web site.

The meeting is hosted by three world-class Scottish research institutes and the University of Edinburgh: the Roslin Institute; the Institute of Genetics and Molecular Medicine and the Beatson Institute for Cancer Research. All three Institutes are world-renowned for producing top quality science at the forefront of biomedical research. The TT meeting visits the UK for the first time following the previous TT meetings in Guangzhou, China (TT2013); Florida, USA (TT2011); Berlin, Germany (TT2010); Toronto, Canada (TT2008); Brisbane, Australia (TT2007) and Barcelona, Spain (TT2005). This will be the 12th meeting in the series, originally pioneered by Johannes Wilbertz (Karolinska Institute, Stockholm, Sweden) in 1999. Since the foundation of the ISTT in 2006, the TT meetings have been the main event sponsored by the Society.

The following speakers have confirmed their participation at the TT2014 meeting:

  • David Adams, Wellcome Trust Sanger Institute, Hinxton, Cambridge UK
  • Ignacio Anegon, Center for Research in Transplantation and Immunology, Nantes, France
  • Stephen Ekker, Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA
  • Kat Hadjatonakis, Developmental Biology Program, Sloan-Kettering Institute, New York, USA
  • Coenraad Hendriksen, Institute for Translational Vaccinology, Bilthoven, The Netherlands
  • Rudolf Jaenisch, Whitehead Institute for Biomedical Research, Nine Cambridge Center Cambridge, USA
  • Jos Jonkers, Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
  • Keith Joung, Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
  • Alex Joyner, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
  • Koichi Kawakami, Division of Molecular and Developmental Biology, National Institute of Genetics, Shizuoka, Japan
  • Jim Murray, Department of Animal Science and Department of Population Health and Reproduction, University of California, Davis, California, USA
  • Stephen Murray, The Jackson Laboratory, Bar Harbor, Maine, USA
  • Lluis Montoliu, ISTT President, Organising Committee, National Center of Biotechnology (CNB), CSIC, Madrid, Spain
  • Vasilis Ntziachristos, Technische Universität Mu?nchen, Munich, Germany
  • Pawel Pelczar, Institute of Laboratory Animal Science, Zürich, Switzerland
  • Janet Rossant, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
  • Angelika Schnieke, Livestock Biotechnology, WZW Center of Life Science, Freising-Weihenstephan, Germany
  • Kai Schönig, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany
  • Austin Smith, Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK
  • Sara Wells, MRC Harwell, Oxfordshire, UK
  • Jacqui White, Wellcome Trust Sanger Institute, Hinxton, Cambridge UK

At the TT2014 meeting, the ISTT will be awarding the 10th ISTT Prize for outstanding contributions to the field of transgenic technologies to Prof. Janet Rossant (The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada). The ISTT Prize is generously sponsored by genOway.

At the TT2014 meeting, the ISTT will be also awarding the 3rd ISTT Young Investigator Award, generously sponsored by inGenious Targeting Laboratory. The ISTT Young Investigator Award recognizes outstanding achievements by a young scientist who will keep the field of transgenic technologies vibrant with new ideas and who has recently received his or her advanced professional degree.

At the TT2014 meeting, and for the first time, the ISTT Best Poster Awards, traditionally awarded to the best posters presented at the corresponding TT meeting, will be generously sponsored by Charles River.

Accepted abstracts submitted for the TT2014 meeting, will be published in the scientific journal Transgenic Research (Springer), to which the ISTT is associated.

A minimum of six registration awards for ISTT members will be sponsored by the International Society for Transgenic Technologies. Applications should be sent, along with the registration document to istt@transtechsociety.org by June 30, 2014. Award decisions will be communicated by July 15, 2014 and awardees will receive a diploma at the TT2014 Meeting.

Important deadlines:

  • Abstract submission deadline June 30, 2014
  • Application for ISTT registration awards deadline June 30, 2014
  • Awards to be communicated by July 15, 2014
  • Early Bird registration fee deadline July 31, 2014
  • Standard Rate registration fee from August 1, 2014
  • Late & On-Site Rate registration fee from September 22, 2014

As it is stated in the TT2014 meeting home page: “Scotland prides itself on both its life science research and the warm welcome given to visitors and looks forward to hosting TT2014“. Therefore, on behalf of the ISTT and of the TT2014 Organising Committee we invite you all to attend to the TT2014 meeting.

See you all in Edinburgh!


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